Radiation necrosis is a potential side effect of radiation therapy used in the treatment of cancer. It occurs when high doses of radiation damage healthy tissue in addition to cancerous cells, leading to cell death and tissue damage. Symptoms of radiation necrosis can include headaches, cognitive impairment, seizures, and changes in mood or behavior. Treatment options for radiation necrosis may include medications, surgery, or hyperbaric oxygen therapy. Researchers are actively studying ways to prevent, diagnose, and treat radiation necrosis to improve the quality of life for cancer patients undergoing radiation therapy.